explain factors effecting Bio compatability

The factors that effect bio compatability are as
follows:

biomaterials interact with the human body and
eventually how those interactions determine the clinical success of a medical
device (such as pacemaker, hip replacement or stent). Modern medical devices and
prostheses are often made of more than one material so it might not always be sufficient
to talk about the biocompatibility of a specific
material.

The immune response and repair functions in the
body are so complicated it is not adequate to describe the biocompatibility of a single
material in relation to a single cell type or
tissue.

Biomaterials can generally be produced either in
nature or synthesized in the laboratory using a variety of chemical approaches utilizing
metallic components or ceramics. They are often used and/or adapted for a medical
application, and thus comprises whole or part of a living structure or biomedical device
which performs, augments, or replaces a natural functions, so to say what the effect of
each bio compatibility is , it differs,  because the elements and the process of it
being made is altered.