ADH or antidiuretic hormone is produced in the
hypothalamus and secreted from the neurohypophysis (posterior pituitary gland). ADH
increases the reabsorption of water from the urine in the renal system back into the
blood. This increases intravascular fluid volume and decreases the amount of urine
voided out of the body. Thus ADH conserves water in the kidneys and returns that fluid
back to the general circulation. This conservation of urine acts to increase blood
pressure because total intravascular fluid volume is
increased.
In a condition called diabetes insipidus, the
hormone ADH is secreted in smaller amounts (hyposecreted), thus causing an increase in
urine volume voided out of the body. People with DI may void thousands of ml/cc in urine
volume. This of course causes other serious problems like
hypotension.
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