Zollinger Ellison syndrome is a disorder which
is characterized by the presence of multiple and recurrent ulcers in the stomach and
duodenum. Zollinger Ellison syndrome is associated, especially, with a local
inflammation, with diarrhea and a steatorrhea (the presence of fats in
faeces).
Zollinger-Ellison syndrome entails sometimes,
after several years, the appearance of metastases in the liver. Zollinger-Ellison
syndrome is either acquired and isolated, or the part of multiple endocrine neoplasia (a
hereditary disease characterized by a hyper-function of several
glands).
These rare disorders are caused by an excessive
gastric acidity, that is caused by the hypersecretion of a digestive hormone,
gastrin.
The medication brakes the acid secretion of the
gastric cells, allowing the healing of the ulcers. It is envisaged the surgical removal
of tumors, associated with chemotherapy, in case of metastases.
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