When a cell is about to divide, the chromosomes have
coiled and thickened and are visible. At other times in the cell's life cycle, they are
not able to be visualized. A cell can be arrested during cell division by applying
colchichine. The chromosomes are stained, usually with Giemsa stain. When preparing a
karyotype, a cell's 23 pairs of chromosomes are microphotographed and a chart is made
with the chromosomes arranged by size and position of centromeres for pairs 1 through
22. The 23rd pair is the sex chromosomes which are either XX or
XY.
Sunday, August 23, 2015
Why can karyotyping be carried out only on cells about to divide?
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