Tuesday, December 30, 2014

How the enzyme function in the liver would be affected in a person with cirrhosis?

Cirrhosis of the liver is a chronic disease that adversely
affects the overall physiology of the organ. The liver has many important functions, one
function is detoxifying the blood before the blood enters systemic
circulation.


Enzymes are chemical catalyst's that assist
biochemical reactions in the body. When the liver is damaged, as in cirrhosis, the
number of liver enzymes are elevated because the enzymes are trying to make the organ
function normally. There are many liver enzymes, one of which is SGOT (serum glutamic
oxaloacetic transaminase). SGOT levels rise dramatically in the presence of liver
disease. Enzyme levels rise when the hepatic cells and tissues are
damaged.


Even though the number of liver enzymes are
elevated in cirrhosis, they are unable to complete their function due to the state of
disease.

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